Doebner modification
English edit
Etymology edit
Named after O. Doebner, who published on the topic in 1902.
Proper noun edit
the Doebner modification
- (chemistry) A variant of Knoevenagel condensation in which one of the withdrawing groups on the nucleophile is a carboxylic acid, and the condensation product undergoes a subsequent decarboxylation step, the base being pyridine.
- Synonym: Doebner condensation