Last modified on 20 August 2014, at 14:01

MPTP

EnglishEdit

PronunciationEdit

  • (file)

InitialismEdit

MPTP

  1. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

NounEdit

MPTP (uncountable)

  1. (neurotoxicology) A byproduct of synthetic heroin, or MPPP, which causes Parkinsonian symptoms in users.
  2. (neurotoxicology) A neurotoxin which degrades into MPP+ after crossing the blood brain barrier, which causes a degredation of the dopaminergic neurons within the substantia nigra.

QuotationsEdit

  • 2005 Dec 29 Petzinger, et al. Journal of Neuroscience Research [1]
    The neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine MPTP provides an excellent opportunity to study repair and response to injury in the basal ganglia.