MPTP

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      Initialism

      MPTP

      1. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

      Noun

      MPTP (uncountable)

      1. (neurotoxicology) A byproduct of synthetic heroin, or MPPP, which causes Parkinsonian symptoms in users.
      2. (neurotoxicology) A neurotoxin which degrades into MPP+ after crossing the blood brain barrier, which causes a degredation of the dopaminergic neurons within the substantia nigra.

      Quotations

      • 2005 Dec 29 Petzinger, et al. Journal of Neuroscience Research [1]
        The neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine MPTP provides an excellent opportunity to study repair and response to injury in the basal ganglia.
      Last modified on 8 June 2013, at 00:00