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Etymology edit

cranio- +‎ schisis.

Noun edit

cranioschisis (plural cranioschises)

  1. A developmental birth defect in which the cranium fails to close completely, so that the brain is exposed to the amnios and eventually degenerates, causing anencephaly.
    • 1953, Biochemical Institute Studies, Issue 5, Biochemical Institute (of the University of Texas), page 51,
      E. M. Butt et al. have reported the production of meningoceles and cranioschises in chick embryos with 0.5 to 1.0 mg. of lead nitrate (21).
    • 1960, Roy Richard Grinker, Neurology, Charles C. Thomas, page 174:
      The partial cranioschises include cranium bifidum occultum, meningocele and meningoencephalocele.
    • 2014, Philip B. Gorelick, Fernando Testai, Graeme Hankey, Joanna M. Wardlaw, editors, Hankey's Clinical Neurology, 2nd edition, Taylor & Francis (CRC Press), page 210:
      It[anencephaly] is the most frequent of the cranioschises.

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