English edit

Alternative forms edit

Etymology edit

Shortened from Jarisch-Herxheimer reaction, which in turn derives from the names of Adolf Jarisch and Karl Herxheimer, physicians who separately described the reaction in syphilis patients.

Verb edit

herx (third-person singular simple present herxes, present participle herxing, simple past and past participle herxed)

  1. (medicine, informal) To experience a Jarisch-Herxheimer reaction, a negative reaction to antibiotic treatment.
    • 2017 October 1, Edward McSweegan, “Lyme Disease: Questionable Diagnosis and Treatment”, in ActionLyme.org[1]:
      These usually last for several hours, and require little more than aspirin and bed rest. Yet many Lyme newsgroup participants write about a "herx" beginning days or weeks after the start of antibiotic therapy, and "herxing" for weeks at a time -- often in a cyclic fashion.
    • 2020, John Coleman, Rethinking Parkinson’s Disease, page 215:
      When using any antimicrobial against any Lyme-like infection, most patients will herx at some stage.
    • 2021 March 4, Fredsmith, “herxing like crazy on Fenben”, in HealingWell[2]:
      Has anyone else herxed intensely even on low dose fenben?
      I started with 150mg and herxed, backed down to 70mg and still herxed along with my 100mg doxy.

Noun edit

herx (plural herxes)

  1. (medicine, informal) A Jarisch-Herxheimer reaction.

Usage notes edit

  • The informal terms herx and herxing are common in discussions of Lyme disease, especially among patients of the disease and their supporters.