thioguanosine

English

Etymology

thio- +‎ guanosine

Noun

thioguanosine (uncountable)

1. (organic chemistry) The compound 2-amino-6-mercapto-9-(b-D-ribofuranosyl)purine formally derived from guanosine by replacing the guanine by thioguanine
   • 2016 March 4, “PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma”, in PLOS ONE‎^[1], →DOI:

     Several drug classes which are listed top on the list include topoisomerase inhibitors (camptothecin, ellipticine, doxorubicin, etoposide, thioguanine, thioguanosine), multiple histone deacetylase inhibitors (trichostatin A, vorinostat, 5162773, 5186223), PARP inhibitors (1,5-isoquinolinediol, 3-aminobenzamide, phenanthridinone), proteasome inhibitors (MG132, 1,4 chrysenequinone) and cyclin-dependent kinases (CDKs) inhibitors (alsterpaullone, 02974170002B, GW-8510).