CHAPLE syndrome
English edit
Etymology edit
CHAPLE stands for "CD55 deficiency with hyperactivation of complement, angiopathic thrombosis, and severe protein-losing enteropathy".
Noun edit
CHAPLE syndrome (uncountable)
- A rare genetic disorder of the immune system, caused by mutations of the complement regulator CD55 gene, and characterized by severe protein-losing enteropathy leading to hypoproteinemia.