osteocalcin
English edit
Etymology edit
Noun edit
osteocalcin (countable and uncountable, plural osteocalcins)
- (organic chemistry, biochemistry) A protein, found in bone and dentin and manufactured by osteoblasts, that plays a role in mineralization and calcium ion homeostasis.
- 1994, Hideaki Ogura, Pharmacological Approach to the Study of the Formation and the Resorption Mechanism of Hard Tissues, Ishiyaku EuroAmerica, page 134:
- Comparison of the sequences of the various osteocalcins indicates that the central portion of the molecule is highly conserved.
- 2014, Lee B. Smith, William H. Walker, “16: Hormone Signaling in the Testis”, in Tony M. Plant, Anthony J. Zeleznik, editors, Knobil and Neill's Physiology of Reproduction, Elsevier (Academic Press), page 669:
- Osteocalcin has recently been identified as a bone-derived hormone with significant functional impacts on sex steroid production by the testis, completing the circle of mutual interdependence between the skeletal system and gonad (for reviews, see Refs 536–538).
- 2017, Olena V. Andrukhova, Reinhold G. Erben, “11: Kidney—Bone: Interaction”, in Susan Y. Smith, Aurore Varela, Rana Samadfam, editors, Bone Toxicology, Springer, page 349:
- Osteocalcin together with the other Gla-protein MGP belongs to a distinct subgroup of the larger vitamin K-dependent protein family, the constituents of which are primarily involved in blood coagulation.
Translations edit
protein found in bone and dentin, manufactured by osteoblasts
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