1980 —Mark Gorton, "The hitch-hiker's guide to the galaxy", published in New Scientistp. 415
Hmmm, if The Answer is 42, then maybe The Ultimate Question is: "How many version of the the Guide were generated when the digital writing machine (with which author Douglas Adams readily admits collaboration) went completely out of control?"
2006 —Alan Lucas, Hugh A. Sampson, Primary prevention by nutrition intervention in infancy and childhood, p. 254
What I see in the -omics field, in some way including what you said, is that there is promise that if we measure everything we are going to have an answer, and the answer is 42 for those of you who haven't read the book.
2007 —Adrian Mackay, Recruiting, Retaining and Releasing People: Managing Redeployment, Return, Retirement and Redundancy, p. 244
The history of mankind has always been about the search of some answer to the meaning to life — The Hitchhiker's Guide to the Galaxy enthusiasts know the answer is 42 — but today we are looking for ‘meaning’ in the workplace.
2008 — Jon Rasmussen, Dreaming Your World Into Being: The Shaman's Secrets to Having the Life You Desire Now, p. 72
So here it is, the answer is 42... told you that you wouldn't like it. No, that was the computer's answer; my answer is joy, fun, feeling good.