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auto- +‎ repression


autorepression (uncountable)

  1. (genetics, biochemistry) repression of the expression of a protein by the protein itself
    • 2015 August 13, “Binding of the Lactococcal Drug Dependent Transcriptional Regulator LmrR to Its Ligands and Responsive Promoter Regions”, in PLOS ONE[1], DOI:10.1371/journal.pone.0135467:
      An incomplete PadR motif is located in the p/o of lmrR, this palindromic sequence is only weakly recognized by LmrR. A proposed mechanism for the binding of LmrR to the p/o regions and the regulation of lmrCD and lmrR is as followed: the binding of two LmrR dimers to PlmrCD, together with an extensive binding of PlmrR by multiple LmrR dimers, results in a repression of lmrCD and a strong autorepression of lmrR.