clobenpropit

English

The structural form of a clobenpropit molecule.

Noun

clobenpropit (uncountable)

1. (biochemistry) A histamine H₃ antagonist that has neuroprotective effects via stimulation of GABA release in the brain. Chemical symbol: C₁₄H₁₇ClN₄S.

References

• Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P (2007) “The human histamine H3 receptor couples to GIRK channels in Xenopus oocytes”, in Eur. J. Pharmacol., volume 567, number 3, →DOI, →PMID, pages 206–10
• Dai H, Fu Q, Shen Y, Hu W, Zhang Z, Timmerman H, Leurs R, Chen Z. (2007 June 1) “The histamine H3 receptor antagonist clobenpropit enhances GABA release to protect against NMDA-induced excitotoxicity through the cAMP/protein kinase A pathway in cultured cortical neurons.”, in European Journal of Pharmacology, volumes 563(1-3), →PMID, pages 117-23