English edit

Etymology edit

colono- +‎ sphere

Noun edit

colonosphere (plural colonospheres)

  1. (pathology) A colonic spheroid
    • 2015 April 14, Hao Liu et al., “Overexpression of PP2A inhibitor SET oncoprotein is associated with tumor progression and poor prognosis in human non-small cell lung cancer”, in Oncotarget[1], volume 6:
      It has been shown that SET knockdown was shown to negatively affect tumorigenesis in CML [ 32 ], and silence of SET with siRNAs in CRC cell lines induced a decrease in the cell growth and colonosphere formation ability in both number and size of the spheres formed [ 25 ].