cotargeting
English edit
Etymology edit
Noun edit
cotargeting (uncountable)
- The targeting of two things at the same time
- 2015 August 6, Ki Bom Kim et al., “Clinical effect of abiraterone acetate in Korean patients with metastatic castration-resistant prostate cancer according to duration of androgen deprivation therapy”, in Korean Journal of Urology[1], volume 56, :
- Preclinical evidence that androgen biosynthesis in prostate cancer cells does not necessarily follow a single dominant pathway and that residual androgens or alternative ligands (including administered glucocorticoids) can reactivate androgen receptor signaling support the cotargeting of more than one enzyme involved in steroidogenesis and combining a CYP17A1 inhibitor with an antiandrogen.