dysmegakaryocytopoiesis
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dysmegakaryocytopoiesis (uncountable)
- (medicine) Dysfunctional megakaryocytopoiesis; defective maturation of bone marrow progenitor cells into megakaryocytes.
- 1985, Grover C. Bagby, The Preleukemic Syndrome (Hemopoietic Dysplasia), CRC PressI Llc
- The marrow also showed megakaryocytosis and severe dysmegakaryocytopoiesis with numerous micromegakaryocytes and micromegakaryoblasts.
- 1989, Stuart Roath, M. Corn, Current Approaches to Bone Marrow Histopathology, CRC Press, →ISBN, page 109:
- In addition, dysmegakaryocytopoiesis, iron-laden macrophages, plasma cells and lymphoid infiltrates might be better identified in histologic sections.
- 1994, John F. Foley, Julie M. Vose, James O. Armitage, Current Therapy in Cancer, W B Saunders Company, →ISBN:
- Dysmegakaryocytopoiesis may include hypolobulated, hyperlobulated, or multinucleated megakaryocytes, or a reduction in their number or size.
- 2011, Richard A. McPherson, Matthew R. Pincus, Henry's Clinical Diagnosis and Management by Laboratory Methods, Elsevier Health Sciences, →ISBN, page 622:
- Dysmegakaryocytopoiesis includes large megakaryocytes with unsegmented nuclei, micromegakaryocytes, and megakaryocytes with two or more small, unconnected nuclei. Megakaryocytes may be decreased in number.
- 2013, Victor S. Blanchette, Vicky R. Breakey, Shoshana Revel-Vilk, SickKids Handbook of Pediatric Thrombosis and Hemostasis, Karger Medical and Scientific Publishers, →ISBN, page 31:
- Moderate thrombocytopenia due to dysmegakaryocytopoiesis, platelet dysfunction, reticulocytosis, and globin synthesis imbalance resembling beta-thalassemia have been described among patients with X-linked thrombocytopenia with beta-thalassemia.
- 1985, Grover C. Bagby, The Preleukemic Syndrome (Hemopoietic Dysplasia), CRC PressI Llc