homodimerisation

English

Noun

homodimerisation (plural homodimerisations)

1. Alternative form of homodimerization
   • 2015 December 24, “Revealing Different Roles of the mTOR-Targets S6K1 and S6K2 in Breast Cancer by Expression Profiling and Structural Analysis”, in PLOS ONE‎^[1], →DOI:

     IGF1 and IGF2 bind and activate the receptor tyrosine kinase IGF1R, leading to homodimerisation as well as heterodimerisation with the insulin receptor (INSR), subsequent IRS1 recruiting and downstream PI3K/AKT/mTOR activation.