hydroxyamide
English
editEtymology
editNoun
edithydroxyamide (plural hydroxyamides)
- (organic chemistry) The amide of a hydroxy acid
- 2015 May 22, Vidhya R. Rao et al., “Voltage-Gated Ion Channels in Cancer Cell Proliferation”, in Cancers[1], volume 7, :
- Novel hydroxyamide compounds developed using rational drug designing approaches, based on the binding site of phenytoin to VGSCs, have demonstrated significant inhibition of voltage-gated sodium channel activities and increased inhibition of androgen–independent prostate cancer cell growth in vitro in comparison to phenytoin and significant ability to reduce prostate cancer in vivo as well [ 124, 158 ].