hypergalactosylated

English

Etymology

hyper- +‎ galactosylated

Adjective

hypergalactosylated (not comparable)

1. Excessively galactosylated
   • 2015 December 12, “Multi-Angle Effector Function Analysis of Human Monoclonal IgG Glycovariants”, in PLOS ONE‎^[1], →DOI:

     We demonstrate a clear impact of glycosylation pattern on antibody stability and interaction with different FcγRs. Consistent with previous reports, deglycosylated antibodies failed to bind all Fcγ-receptors, with the exception of high affinity FcγRI. The FcγRII and FcγRIIIa binding activity of IgG1 was observed to depend on the galactosylation level, and hypergalactosylated antibodies demonstrated increased receptor interaction.