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iPSC (plural iPSC or iPSCs)

  1. (biology) Initialism of induced pluripotent stem cell.
    • 2009, Essentials of stem cell biology, edition 2, Robert Paul Lanza (editor), page 30:
      The fact that only a small fraction of cells infected with the reprogramming factors form iPSC colonies indicates that direct reprogramming is a stochastic process.
    • 2010, Michael Roßbach, Manal Hadenfeld, and Oliver Brüstle, Industrial Applications of Stem Cells, in Translational Stem Cell Research: Issues Beyond the Debate, Kristina Hug, Göran Hermerén (editors), page 91:
      One of the most promising routes in this regard is the generation of induced pluripotent stem cells (iPSC) by reprogramming cells.
    • 2010, G. Sun et al, in Biomaterials as Stem Cell Niche, Krishnendu Roy (editor), page 202:
      ECs Derived from ESC and iPSC
    • 2011, M. A. Hayat (editor), Stem Cells and Cancer Stem Cells: Therapeutic Applications in Disease and Injury, volume 1, page 10:
      [...] the propensity of stem cells to form teratoma following transplantation is still another major obstacle in using iPSC for disease therapy.
    • 2015, Paull, D. et al., "Automated, high-throughput derivation, characterization and differentiation of induced pluripotent stem cells", Nature Methods, vol. 12, no. 9, pg. 885 (abstract):
      The preparation of somatic cells, their reprogramming and the subsequent verification of iPSC pluripotency are laborious, manual processes [....]


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