shotgun proteomics

English

Noun

shotgun proteomics (uncountable)

1. (genetics) A laboratory method for the determining the identities of proteins in a mixture.
   • 2005, Selene K Swanson, P. Michael, “The continuing evolution of shotgun proteomics”, in Drug Discovery Today:

     Analogous to (shotgun sequencing), in shotgun proteomics, complex protein mixtures are digested into peptides, analyzed by tandem mass spectrometry, and computer algoriths then map the peptides onto proteins to determine the original content of the mixture.