centroblast

English

Etymology

centro- +‎ -blast

Pronunciation

• IPA^(key): /ˈsɛntɹəblæst/, /-blɑːst/

Noun

centroblast (plural centroblasts)

1. (anatomy) An activated B cell that is enlarged with multiple eccentric nucleoli and proliferating in the germinal center of a secondary lymphoid follicle, after stimulation by follicular dendritic cell cytokines and helper T cells.
   • 1975, K Lennert, “Morphology and classification of malignant lymphomas and so-called reticuloses”, in Malignant Lymphomas of the Nervous System:

     Therefore we proposed the term centroblast instead of germinoblast and the term centrocyte instead of germinocyte.

Derived terms

• centroblastic

See also

• centrocyte