with every fiber of one's being

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with every fiber of one's being

  1. To the fullest extent possible.
    • 1900, Joseph Conrad, Lord Jim, page xxxv. 244:
      The girl was righ - there was a sign, a call in them - something to which I responded with every fibre of my being.
    Synonyms: with every bone in one's body, with every ounce of one's being