English edit

Noun edit

coordinome (plural coordinomes)

  1. (music) A form of punched tape reader for a synthesizer
  2. (biochemistry) A DNA sequence that serves to coordinate the expression of two or more genes.
    • 2003, Cancer Research - Volume 63, page 4123:
      Second, only in one pair (cMM17-MM17) the expression levels of most coordinome members were similar in melanocyte and melanoma cultures (Figs. 4 and 5).
    • 2012, Silvia Lorenzi, Matteo Forloni, Loredana Cifaldi, Chiara Antonucci, Arianna Citti, Renata Boldrini, Marco Pezzullo, Aurora Castellano, Vincenzo Russo, Pierre van der Bruggen, Patrizio Giacomini, Franco Locatelli, Doriana Fruci, “IRF1 and NF-kB restore MHC class I-restricted tumor antigen processing and presentation to cytotoxic T cells in aggressive neuroblastoma”, in PLoS One, volume 7, number 10:
      The present results support the original suggestion that MHC-I and APM components act as a coordinome with core and peripheral (gene-specific) control features, and a hierarchy of control steps [41].