English edit

Etymology edit

Equivalent to granulo- +‎ -pexy. Borrowed from French granulopexie, coined by Biozzi et al. in 1948, following work by Nicholas Jancsó, who noted that injection of histamine causes endothelial cells to pick up stray particles.[1][2]

Noun edit

granulopexy (uncountable)

  1. (immunology) The fixation of granules circulating in the blood, most notably by the reticuloendothelial system.
    • 1968, International Series of Monographs on Pure and Applied Biology: Division, Zoology[2], Pergamon Press, page 212:
      It is possible that fixation of granules (granulopexy) is partly as a result of attraction when phagocytes are in contact with solid structures (thigmo-reaction)
    • 1969, Fondazione Carlo Erba, Medicine, Biology, and Surgery at the Carlo Erba Foundation: Proceedings of the First 5 Years' Symposia[3], Carlo Erba Foundation, page 1014:
      granulopexy may be observed sometimes in cells that do not belong to the R.E.S.: for example, we all know that liver and kidney cells can appropriate some particulate dyestuffs

Derived terms edit

References edit

  1. ^ Guido Biozzi, G. Mené, Zoltan Ovary (1948) “L'histamine et la granulopexie de l'endothélium vasculaire”, in Rev. immunol., volume 12, Paris
  2. ^ M. Rocha E Silva, J. Garcia Leme (2013 October 22) Chemical Mediators of the Acute Inflammatory Reaction: International Series of Monographs in Pure and Applied Biology: Modern Trends in Physiological Sciences[1], Elsevier, →ISBN, page 30:This interesting effect of histamine was confirmed by Toro (1942) and submitted to extensive investigation by Biozzi et al. (1948, 1951) (see Halpern, 1959) with the name of “granulopexy”.