motexafin

English edit

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motexafin

(medicine) an inhibitor of thioredoxin reductase and ribonucleotide reductase
- 2016 March 2, “Brain Radiotherapy plus Concurrent Temozolomide versus Radiotherapy Alone for Patients with Brain Metastases: A Meta-Analysis”, in PLOS ONE‎^[1], →DOI:
  The meta-analysis of Qin et al [12 ] confirmed that the combination of WBRT plus chemotherapy (including TMZ, carboplatin, and motexafin gadolinium) may increase treatment response rates in patients with BM, therefore TMZ combined with RT can be a reasonable treatment option for patients with BM. However, follow-up studies conclude that the addition of TMZ to RT does not improve survival and has an increased incidence of adverse events compared with RT alone [13 ,14 ].