senolysis
English
editEtymology
editNoun
editsenolysis (countable and uncountable, plural senolyses)
- (medicine) The destruction of senescent cells, such as to alleviate age-related diseases.
- 2020, Joanne Laycock, et al., 7: The Role of Chronic Kidney Disease in Ectopic Calcification, Elena Aikawa, Joshua D. Hutcheson (editors), Cardiovascular Calcification and Bone Mineralization, Springer (Humana Press), page 156,
- These strategies[to target senescent cells] consist of senolysis, immune-mediated senescent cell clearance and SASP neutralisation.
- 2022, Franziska Kellers, et al., Senescence-Associated Molecules and Tumor-Immune-Interactions as Prognostic Biomarkers in Colorectal Cancer, Arndt Hartmann, Luca Di Tommaso (editors), Rising Stars 2021: Pathology, Frontiers in Medicine, page 46,
- This immune cell-mediated senolysis seems to be facilitated via direct cell-cell contact inducing apoptosis and granule exocytosis.
- 2023, Jan O. Nehlin, Chapter 7: Senolytic and senomorphic interventions to defy senescence-associated mitochondrial dysfunction, Ufuk Çakatay, Mehmet Can Atayik (editors), Advances in Protein Chemistry and Structural Biology, Volume 135, Elsevier (Academic Press), page 224,
- 2020, Joanne Laycock, et al., 7: The Role of Chronic Kidney Disease in Ectopic Calcification, Elena Aikawa, Joshua D. Hutcheson (editors), Cardiovascular Calcification and Bone Mineralization, Springer (Humana Press), page 156,
Related terms
editTranslations
editdestruction of senescent cells
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