spectraplakin
English edit
Etymology edit
(This etymology is missing or incomplete. Please add to it, or discuss it at the Etymology scriptorium.)
Noun edit
spectraplakin (plural spectraplakins)
- (biochemistry) Any of a group of exceptionally long, intracellular proteins that have the rare ability to bind to all three cytoskeletal elements: actin, microtubules, and intermediate filaments
- 2016 February 18, “Cytoskeletal Linker Protein Dystonin Is Not Critical to Terminal Oligodendrocyte Differentiation or CNS Myelination”, in PLOS ONE[1], :
- Thus it is possible that in Schwann cells, Dst is involved in any or all of intermediate filament organization, basement membrane formation and mediation of signaling of specific integrin complexes—none of which are present in OLs. Further explanation may exist for the seemingly disposable nature of neuronal Dst in OLs. In mammals, a second member of the spectraplakin exists: microtubule-actin crosslinking factor 1 (Macf1; variantly actin crosslinking family 7/Acf7).