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Etymology

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From German Kataplexie, from Ancient Greek κατάπληξις (katáplēxis).

Pronunciation

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Noun

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cataplexy (countable and uncountable, plural cataplexies)

  1. (medicine) An abrupt loss of muscle tone, sometimes associated with narcolepsy.
    • 2013 May 1, James M. Parish MD, FCCP, “Genetic and Immunologic Aspects of Sleep and Sleep Disorders”, in Chest[1], volume 143, number 5, →DOI, pages 1489–1499:
      Narcolepsy has been associated with the human leukocyte antigen (HLA) system, a 4-megabase region of chromosome 6, which is divided into three subregions: class I, class II, and class III. Class II HLA antigens have been strongly associated with autoimmune diseases. The class II antigen, DQB1*0602, has been associated with narcolepsy. Most (90%-100%) patients with narcolepsy/cataplexy across all ethnic groups have this allele. In addition, 35% to 56% of patients who have narcolepsy without cataplexy also have this allele. However, 20% of the normal population also has the allele, reducing its usefulness in diagnostic testing.

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Further reading

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  • cataplexy”, in OneLook Dictionary Search.