eigengene

English

Eigengenes following Alter et al. PNAS 2000 and Alter and Golub PNAS 2006

Etymology

From eigen- +‎ gene.

Noun

eigengene (plural eigengenes)

1. (genetics) (mathematics) (physics) One of a set of right singular vectors of a genes x samples matrix that tabulates, e.g., the mRNA or gene expression of the genes across the samples.
   • 1999, Orly Alter et al., ‘‘Singular Value Decomposition for Gene Expression Data Processing and Modeling.’’ In: After the Genome V (October 6–10, 1999, Jackson Hole, WY), published by the U.S. Department of Energy (DOE) Office of Scientific and Technical Information (OSTI).

     We describe the use of singular value decomposition in transforming gene expression data from genes/arrays space to ‘‘eigengenes’’/‘‘eigenarrays’’ space, where the eigengenes and eigenarrays are unique orthonormal superpositions of the genes and arrays, respectively.

Quotations

• For quotations using this term, see Citations:eigengene.

Related terms

• eigengenome