hepcidin
English edit
Etymology edit
From hep(ato)- (“liver”) + -cide (“killing”) + -in (“compound”), because of its origin and bacteria-killing properties.
Noun edit
hepcidin (usually uncountable, plural hepcidins)
- A hormone produced by the liver that regulates iron homeostasis in mammals.
- 2008 November 26, Masako Kohyama, Wataru Ise, Brian T. Edelson, Peter R. Wilker, Kai Hildner, Carlo Mejia, William A. Frazier, Theresa L. Murphy, Kenneth M. Murphy, “Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis”, in Nature, volume 457, number 7227, :
- The known genetic defects of iron metabolism 14, 25, 26 frequently involve proteins that function as iron transporters/exporters (for example, ferroportin 18), as receptors for iron-binding proteins (for example, transferrin receptor 27 and hemochtomatosis 28), or to regulate the activity of these transporters or receptors (for example, hepcidin 29).