plicamycin
English
editAlternative forms
editEtymology
editFrom translingual (Streptomyces) plica(tus) + -mycin (“antibiotic derived from Streptomyces”).
Pronunciation
edit- (General American) IPA(key): /ˌplaɪ.kəˈmaɪ.sn̩/
Noun
editplicamycin (uncountable)
- (pharmacology) An antibiotic C52H76O24 with antineoplastic activity which is produced by three bacteria of the genus Streptomyces (Streptomyces argillaceus, Streptomyces tanashiensis, and Streptomyces plicatus), acts by inhibiting DNA transcription and replication, and is administered intravenously especially in the treatment of malignant tumors of the testes or in the treatment of hypercalcemia and hypercalciuria associated with advanced neoplastic disease.
References
edit- “mithramycin”, in Lexico, Dictionary.com; Oxford University Press, 2019–2022.
- “plicamycin”, in Merriam-Webster Online Dictionary, Springfield, Mass.: Merriam-Webster, 1996–present.