polypharmacology
English
editEtymology
editFrom poly- + pharmacology.
Noun
editpolypharmacology (plural polypharmacologies)
- The presence of multiple pharmacologies (targets, modes of action etc) in a single drug
- 2015 July 16, “Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays”, in PLOS ONE[1], :
- While several classes of kinase inhibitors are highly selective (MEK, covalent modifying kinase inhibitors) many possess a vast polypharmacology across the kinome target-scape.