tacrine

EnglishEdit

 
Structure of tacrine
 
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EtymologyEdit

From t(etrahydro) +‎ acr(id)ine.

PronunciationEdit

NounEdit

tacrine (uncountable)

  1. (pharmacology) A synthetic drug used in Alzheimer's disease to inhibit the breakdown of acetylcholine by cholinesterase and thereby enhance neurological function.
    • 2007 February 8, Jeremy Pearce, “Leon J. Thal, Neurologist Who Led Study for Alzheimer’s Drugs, Dies at 62”, in New York Times[1]:
      In the 1980s, Dr. Thal, a neurologist, helped lead successful clinical trials of tacrine, a cholinesterase inhibitor drug that was approved by the Food and Drug Administration in 1993.

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