odontomalacia
English edit
Etymology edit
Noun edit
odontomalacia (uncountable)
- (medicine, pathology) Abnormal softening of the teeth.
- 1985, The year book of endocrinology, page 140:
- Professor J. Erdheim in 1906 showed that, from the time the parathyroids were removed from rats, the newly laid down dentinoid was no longer calcified. Odontomalacia (if there is any such word) developed.
- 2017 February, Tchilalo Boukpessi, Betty Hoac, Benjamin R.Coyac, Thibaut Leger, Camille Garcia, Philippe Wicart, Michael P. Whyte, Francis H. Glorieux, Agnès Linglart, Catherine Chaussain, Marc D. McKee, “Osteopontin and the dento-osseous pathobiology of X-linked hypophosphatemia”, in Bone, volume 95:
- Osteomalacia and odontomalacia in XLH have increased osteopontin in the matrix.
- 2017 October, Benjamin R.Coyac, Guillaume Falgayrac, Brigitte Baroukh, Lotfi Slimani, Jérémy Sadoine, Guillaume Penel, Martin Biosse-Duplan, Thorsten Schinke, Agnès Linglart, Marc D. McKee, Catherine Chaussain, Claire Bardet, “Tissue-specific mineralization defects in the periodontium of the Hyp mouse model of X-linked hypophosphatemia”, in Bone, volume 103:
- Skeletal complications in XLH patients include rickets and osteo/odontomalacia, with clinical manifestations including delayed walking, leg bowing (genu varum) or knock knees (genu valgum), growth failure and dental issues such as the occurrence of “spontaneous” tooth abscesses in the absence of caries or trauma.