spliceosome

English

Alternative forms

• splicosome

Etymology

splice +‎ -o- +‎ -some

Pronunciation

• IPA^(key): /ˈsplaɪsioʊˌsoʊm/, /ˈsplaɪsəˌsoʊm/

Noun

spliceosome (plural spliceosomes)

1. (genetics) A dynamic complex of RNA and protein subunits that removes introns from precursor mRNA.
   • 1985 June, Edward Brody, “The "spliceosome": yeast pre-messenger RNA associates with 40S complex in a splicing-dependent reaction”, in Science, volume 228, number 4802, page 963:

     This complex, termed a "spliceosome," is thought to contain components necessary for mRNA splicing; its existence can explain how separated exons on pre-mRNA are brought into contact.

Derived terms

• prespliceosome
• spliceosomal
• supraspliceosome