Philadelphia chromosome

English

The translocation

Etymology

The abnormality was first discovered and described in 1959 by David Hungerford from the Institute for Cancer Research and Peter Nowell from the University of Pennsylvania School of Medicine. Both facilities are located in Philadelphia, Pennsylvania.

Noun

Philadelphia chromosome (plural Philadelphia chromosomes)

1. Human chromosome 22, after it has, pathologically, traded some of its genetic material with chromosome 9; this often causes chronic myelogenous leukemia.

   Synonym: Ph chromosome

Further reading

• Philadelphia chromosome on Wikipedia.Wikipedia