denosumab
English edit
Etymology edit
From arbitrary prefix den- + -os- (“bone”) + -umab (“human monoclonal antibody”).
Pronunciation edit
- (Received Pronunciation) IPA(key): /dɪˈnɒs.jʊ.mab/
- (General American) IPA(key): /dɛnˈoʊ.səˌmæb/, /dəˈnɑs.jəˌmæb/
Noun edit
denosumab (uncountable)
- (pharmacology) A drug (trademarks Prolia and Xgera) that is a genetically engineered monoclonal antibody that reduces bone resorption and increases bone mass by inhibiting osteoclast formation and function and that is administered by injection to prevent fractures associated with osteoporosis and malignant tumors of bone and to treat hypercalcemia associated with various cancers.
References edit
- “denosumab”, in Merriam-Webster Online Dictionary, Springfield, Mass.: Merriam-Webster, 1996–present.