holoprosencephaly
English edit
Etymology edit
From Ancient Greek ὅλος (hólos, “whole”) + πρόσω (prósō, “forwards, onwards”) (referring to the prosencephalon (“forebrain”)) + ἐγκέφαλος (enképhalos, “brain”) + English -y (suffix denoting a condition), i.e. “condition of a whole (inappropriately divided) forebrain”. By surface analysis, holo- + pro- + -s- + encephal- + -y.
Pronunciation edit
- Rhymes: -ɛfəli
Noun edit
holoprosencephaly (countable and uncountable, plural holoprosencephalies)
- (teratology) A congenital disorder involving insufficient division of the lobes of the brain during fetal development, resulting in skull and facial deformities ranging from minor cleft lip problems to cyclopia, in which a single eye develops where the nose would normally be.
Synonyms edit
- HPE (abbreviation)
Hyponyms edit
Coordinate terms edit
- Classifications of holoprosencephaly
- Associated facial deformities
Derived terms edit
- HPE (abbreviation)
Related terms edit
Translations edit
a congenital disorder involving insufficient division of the lobes of the brain
|
References edit
- NINDS Holoprosencephaly Information Page at the (U.S.) National Institutes of Health