(medicine, of a disease or tumour) To spread to other sites in the body; to undergo metastasis.
1989, Margaret Atwood, Cat's Eye:
On other screens are closeups of skin pores, before and after, details of regimes for everything, your hands, your neck, your thighs. Your elbows, especially your elbows: aging begins at the elbows and metastasizes.
2001, David Lodge, Thinks...:
‘Your lump could be a secondary cancer metastasized from the bowel. I had a patient like that not long ago.’