- To make upset or uncomfortable
- Don't unsettle the horses or they'll bolt.
2012 May 9, Jonathan Wilson, “Europa League: Radamel Falcao's Atlético Madrid rout Athletic Bilbao”, in the Guardian:
- Athletic have been showing signs of fatigue domestically and they never quite seemed to reach the same pitch of intensity that had so unsettled Manchester United and Schalke 04 in earlier rounds.
- To bring into disorder or disarray