- (transitive, chiefly passive) To cause (someone) to go insane or become deranged.
- (transitive) To cause disorder in (something); to distort from its ideal state.
- 1776, Adam Smith, The Wealth of Nations:
- Both these kinds of monopolies derange more or less the natural distribution of the stock of the society;
- (archaic) to disrupt somebody's plans, to inconvenience someone; derail.
- 1898, Arthur Conan Doyle, The Lost Special:
- A second special was out of the question, as the ordinary local service was already somewhat deranged by the first.
to cause someone to go insane
to cause disorder in something, to distort it from its ideal state