lyophilization
English edit
Alternative forms edit
Etymology edit
1894, US. lyo- + philos + -ization (alternatively analyzed as lyophilize + -ation), from Ancient Greek λύω (lúō, “to loosen, to dissolve”) + φίλος (phílos, “beloved”) + -ίζειν (-ízein) + Latin -ātiō, due to the dried product being able to rapidly reabsorb the solvent and restore the original substance, hence “lyophil” (solvent-loving). Popularized from 1960 by Louis R. Rey.[1][2] Cognates in other European languages via same construction.
Noun edit
lyophilization (countable and uncountable, plural lyophilizations)
- freeze-drying; the removal of moisture from a frozen material using vacuum
- 1894, United States Department of Agriculture, Crops in Peace and War: The Yearbook of Agriculture (U.S. G.P.O.), p. 74, p. 907:
- After dialysis, the enzyme can be obtained as a dry powder by lyophilization.
- Lyophilization The process of vacuum-drying substances from the frozen state. The water is sublimated into a trap at low temperature or is absorbed by drying agents. Verb: lyophilize.
- 1894, United States Department of Agriculture, Crops in Peace and War: The Yearbook of Agriculture (U.S. G.P.O.), p. 74, p. 907:
Related terms edit
Translations edit
freeze-drying
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References edit
- ^ Lyophilized Biologics and Vaccines: Modality-Based Approaches, 2015, →ISBN, p. 5
- ^ New ventures in freeze drying, L. Rey, Nature, volume 345, pages 185–186 (10 May 1990), “Called lyophilization because it produces dry products that ‘love’ solvents (lyos-philein),”