- (UK) IPA(key): /ɪˈnɒkjuleɪt/
- (General American) IPA(key): /ɪˈnɑːkjuleɪt/
- (General Australian)
- (transitive, immunology) To introduce an antigenic substance or vaccine into something (e.g. the body) or someone, such as to produce immunity to a specific disease. [from c. 1722]
- 1722, John Crawford, The Case of Inoculating the Small-pox Consider'd: And Its Advantages Asserted; in a Review of Dr. Wagstaffe's Letter. Wherein Every Thing that Author Has Advanced Against It, is Fully Confuted: and Inoculation Proved a Safe, Beneficial, and Laudable Practice.:
- But you would not willingly thus give up the Cause; therefore endeavour to draw others into your Assistance, and venture to assert, that by the Account Dr. Nettleton gives, as also by the best Observation upon those who have been Inoculated in this City, scarcely a fourth part of them have had a true and genuine Small Pox.
- (transitive, by extension) To safeguard or protect something as if by inoculation.
- (Can we add an example for this sense?)
- To add one substance to another.
- Synonym: spike
- The culture medium was inoculated with selenium to investigate the rate of uptake.
- To graft by inserting buds. [from c. 1420]
- to inoculate the bud of one tree or plant into another
- to inoculate a tree
- (figuratively) To introduce into the mind (used especially of harmful ideas or principles). [from a. 1600]
- c. 1599–1602, William Shakespeare, “The Tragedie of Hamlet, Prince of Denmarke”, in Mr. William Shakespeares Comedies, Histories, & Tragedies: Published According to the True Originall Copies (First Folio), London: […] Isaac Iaggard, and Ed[ward] Blount, published 1623, OCLC 606515358, [Act III, scene i], line 118, page 265:
- For vertue cannot ſo innocculate our old ſtocke, but we ſhall relliſh of it.
- 1860, John Watts, The Christian Doctrine of Man's Depravity Refuted, Watts & Company, page 14:
- The Church tries to inoculate humanity with the imaginary goodness drawn down from a fabulous heaven, and from a priest-manufactured God.
to provide immunity
to add one substance to another
to graft by inserting buds
to introduce into the mind
- inoculate in Webster’s Revised Unabridged Dictionary, G. & C. Merriam, 1913.
- inoculate in The Century Dictionary, New York, N.Y.: The Century Co., 1911.